Publications Publications by Toxys: McCarrick S et al. (2020) ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (geno)Toxicity Screening of Nanoparticles-Metals, Oxides and Quantum Dots. Nanomaterials (Basel). 2020 Jan 6Sasaki et al. (2020) Application of the adverse outcome pathway framework to genotoxic modes of action. Environ Mol Mutagen. 2020 JanMcCarrick S et al. (2019) High variability in toxicity of welding fume nanoparticles from stainless steel in lung cells and reporter cell lines: the role of particle reactivity and solubility. Nanotoxicology. 2019 Aug 16:1-17Brown DM et al. (2019) The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system. Toxicol In Vitro. 2019 Jul 4Åkerlund E et al. (2018) Genotoxic and mutagenic properties of Ni and NiO nanoparticles investigated by comet assay, γ-H2AX staining, Hprt mutation assay and ToxTracker reporter cell lines. Environ Mol Mutagen 2018Eskes C et al. (2017) Good cell culture practices & in vitro toxicology Toxicol In Vitro. 2017 Apr 24Ates G et al. (2016). The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards. Mutat Res. 2016 Nov 1;810:13-21Nelson BC et al. (2016). Emerging metrology for high-throughput nanomaterial genotoxicology. Mutagenesis. 2016 Aug 26. pii: gew037Hendriks G et al. (2016). The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding. Toxicol Sci. 150, 190–203.Karlsson, HL et al. (2014). Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines. Part Fibre Toxicol 11, 41.Hendriks, G et al. (2013). Cellular-signaling pathways unveil the carcinogenic potential of chemicals. J Appl Toxicol 33, 399–409Hendriks, G et al. (2012). The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals. Toxicol. Sci. 125, 285–298Hendriks, G et al. (2011). Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment. Mutat Res 709-710, 49–59. Publications on ToxTracker: Cappellini et al. (2018) Mechanistic insight into reactivity and (geno)toxicity of well-characterized nanoparticles of cobalt metal and oxides. Nanotoxicology. 2018 Aug 12Mirjam Luijten, Evelyn D. Olthof, Betty C. Hakkert, Emiel Rorije, Jan- Willem van der Laan, Ruud A. Woutersen & Jan van Benthem (2016). An integrative test strategy for cancer hazard identification, Critical Reviews in Toxicology, 46:7, 615-639 Any technical questions left? Do you want to get in contact? Click here!